About Oxbryta and it's recall

Attorneys Marin & Murphy representing sickle cell families in the Oxbryta lawsuit against Pfizer and GBT.
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About Oxbryta and it’s recall

It was 2024 when the news hit, and for families relying on Oxbryta, it felt like a punch to the gut. This sickle cell drug, greenlit by the FDA back in November 2019, was supposed to be a game-changer. Parents everywhere breathed a sigh of relief—finally, something to ease the relentless burden of sickle cell disease. But fast forward to last year, and Pfizer yanked it off the shelves. Why? The answer lies in the clinical trials that came after approval—studies that peeled back the curtain on a troubling truth.

Those trials didn’t just show Oxbryta falling short. They revealed it was actively causing harm. Kids taking it were hit with more vaso-occlusive crises—those brutal episodes where blood flow gets choked off—than anyone could’ve predicted. And the deaths? Higher than in the placebo groups. It was enough to make the FDA sit up and take notice, urging doctors to stop prescribing it cold turkey. For parents who’d pinned their hopes on this drug, the recall wasn’t just a headline—it was personal. Lawsuits started piling up as families demanded answers. At Marin & Murphy, we’re helping to lead the charge in that fight, helping parents turn their pain into action with an Oxbryta lawsuit to hold Pfizer accountable. With over 1,000 families already filing claims, the fight against Pfizer is gaining momentum. Legal timelines are tight, and delaying could mean losing your right to compensation. Act now to join the growing number of victims seeking justice.

Oxbryta victims are claiming compensation now—don’t miss your chance before time runs out. Over 1,000 families already filing claims—join them.

Contact Our Oxbryta Legal Team Now

dangers and side effects of oxbryta

Oxbryta was heralded as a transformative treatment for sickle cell disease, promising enhanced oxygen delivery and reduced complications for children long burdened by this condition. Families embraced that hope with open arms. Yet, subsequent clinical studies revealed a starkly different reality: patients administered Oxbryta experienced worsened outcomes. Incidents of vaso-occlusive crises (VOCs)—severe blockages depriving tissues of oxygen—surged, and mortality rates exceeded those observed in placebo cohorts. Confronted with this alarming evidence, Pfizer swiftly withdrew the drug from circulation and terminated its related research efforts, preempting any formal directive from the FDA.

VOCs inflict profound suffering. Deformed red blood cells obstruct vessels, precipitating excruciating pain, frequent hospitalizations, and enduring damage. For families who relied on Oxbryta’s assurances, the increase in VOCs was not merely a disappointment—it was a profound breach of trust. The consequences are undeniable and severe:

  • Heightened pain from vaso-occlusive crises
  • Elevated mortality rates compared to placebo groups
  • Persistent injuries, including arthritis, renal impairment, and cerebral infarction

The sense of betrayal is palpable. Families entrusted Oxbryta to alleviate the relentless toll of sickle cell disease, only to face amplified hardship. This is the foundation of the Oxbryta litigation. Far beyond assigning blame, this legal action seeks to hold Pfizer accountable for the injuries sustained and to secure just compensation for medical expenses, suffering, and, in tragic instances, wrongful death. If your child has endured harm from this drug, know that you are not isolated in this struggle, nor must you confront it without support.

eligiblity for filing an oxbryta lawsuit

Here’s where you come in. If your child took Oxbryta any time since it launched in 2019, and things went wrong, you’ve got a shot at justice. Maybe it was more VOCs—those hospital-dash moments that broke your heart. Maybe it’s lasting trouble—kidney issues, a stroke, arthritis creeping in too young. Or maybe it’s the worst outcome—a child gone because of a drug that failed them. Parents across the country are stepping up, filing mass tort claims against Pfizer and GBT. You can too.

There’s flexibility here. Some families are joining a class action lawsuit, pooling their strength. Others want a solo fight, tailored to their story. Either way, our lawyers at Marin & Murphy can walk you through it. Nationwide, no exceptions—if you’re in this, we’re with you. But don’t sleep on this. Legal deadlines are real, and they don’t bend. Not sure where you stand? That’s fine. A quick chat with us, no cost, will sort it out.

WHY CHOOSE MARIN & MURPHY FOR YOUR OXBRYTA CASE?

You’re not looking for just any lawyer—you need someone who’s been in the trenches, who gets what’s at stake. That’s us. At Marin & Murphy, we’ve spent decades taking on pharmaceutical companies and winning. Remember Zantac? We tackled its cancer risks head-on. Xeljanz and those blood clot cases? We handled them. Valsartan’s contamination mess? We are still working hard to deliver justice. Big Pharma doesn’t scare us—it motivates us.

Our Contingency Fee Structure: No fee unless there is a recovery

At Marin & Murphy, we believe that everyone deserves access to justice, regardless of their financial situation. The firm advances court costs and litigation expenses, and those expenses are repaid from the recovery. You are not responsible for court costs or litigation expenses if there is no recovery, unless a court directs otherwise. The attorney’s fee is a percentage of the gross recovery, calculated before expenses are deducted. That’s why we offer our services on a contingency fee basis for mass tort cases like the Oxbryta lawsuit. This means you pay no upfront fees, and we only get paid if we successfully recover compensation for you. For a detailed explanation of our fee structure, please visit our Mass Tort Fee Structure page.

For sickle cell parents, this isn’t business as usual. It’s personal. We’ve seen the toll bad drugs take—on kids, on families, on hope. That’s why we’re in this Oxbryta lawsuit fight, bringing everything we’ve got. No upfront costs, no risk—just a team that doesn’t get paid unless you do. Years of standing up to giants like Pfizer mean we know their playbook. Let us use that to your advantage.

Our firm’s won settlements against Pfizer
in the Xeljanz blood clot lawsuits. Your family could be next.

Contact Our Oxbryta Legal Team Now

March 2025 Oxbryta Lawsuit Update

  • March 2025 Update: In March 2025, a federal judge issued a scheduling order for an Oxbryta injury lawsuit, setting the case for trial by summer 2027. This could mark the first federal trial concerning the side effects of the discontinued sickle cell disease drug, highlighting the legal scrutiny surrounding Oxbryta. [See Court Order]
  • February 2025 Update: Pfizer filed a motion to dismiss an Oxbryta class action lawsuit, arguing that the claims are preempted by federal law due to the FDA’s approval of the drug’s labels and that the plaintiffs lack standing under Article III of the U.S. Constitution. [See Motion Details]
  • February 2025 Update: As of February 2025, a total of six Oxbryta lawsuits had been filed in state and federal courts. The litigation remained in its early stages, with no trials yet and pre-trial discovery not yet begun.
  • December 2024 Update: In late 2024, lawsuits filed after the Oxbryta recall accused Pfizer and Global Blood Therapeutics of reckless conduct. One federal complaint alleged that the companies knew about serious safety risks (such as increased vaso-occlusive crises and stroke) but concealed this information from patients and doctors.
  • September 2024 Update: Pfizer announced a voluntary global recall of Oxbryta in September 2024 after post-market studies revealed a higher risk of dangerous side effects (including vaso-occlusive crises, organ failure and death) than previously anticipated. The company acknowledged that Oxbryta’s risks outweighed its benefits, leading to the drug’s withdrawal from the market.

WINNING BLOOD CLOT LAWSUITS:

OUR PROVEN TRACK RECORD AGAINST PFIZER

At Marin & Murphy, we’ve secured settlements against Pfizer for blood clot-related injuries, like those seen in both Xeljanz and Oxbryta cases. Our success in fighting for victims of dangerous clot risks—like the vaso-occlusive crises (VOCs) linked to Oxbryta—shows why we’re the right choice for your family.

Xeljanz Blood Clot Lawsuit: A Six-Figure Settlement for a Clot-Related Injury

Our firm secured a confidential six-figure settlement with Pfizer for a client who suffered a deep vein thrombosis (DVT) — a serious blood clot — after taking Xeljanz. Here’s how we delivered justice:
  • Client: 50-year-old Connecticut resident
  • Prescribed: Xeljanz for ulcerative colitis
  • Usage: Took the drug for just 2 months in 2019
  • Injury: Developed a deep vein thrombosis (DVT)—a life-threatening blood clot
  • Result: Confidential six-figure settlement with Pfizer
This victory underscores our experience as Xeljanz lawyers and our ability to hold Pfizer accountable for clot-related injuries. Now, with Oxbryta recalled due to vaso-occlusive crises (VOCs)—another dangerous clot condition in sickle cell patients—we’re ready to fight for families facing similar risks.

Why This Matters for Oxbryta Victims

Both Xeljanz and Oxbryta have been linked to serious blood clot risks:
  • Xeljanz caused DVT, a clot that forms in deep veins, often in the legs, which can travel to the lungs and become fatal.
  • Oxbryta was recalled after studies showed it increased vaso-occlusive crises (VOCs)—painful episodes where sickle-shaped cells block blood flow, causing tissue damage and organ failure.
Though VOCs and DVT are different, both involve dangerous clotting that can devastate lives. Our firm’s success in securing settlements for clot-related injuries — like the Xeljanz case — proves we understand the science and the stakes. If your family has been harmed by Oxbryta, we’re here to help you hold Pfizer accountable.
Injured by Oxbryta’s clot risks? Contact us for a free consultation and let our experienced team fight for your Pfizer settlement—just like we did for Xeljanz victims.

Disclaimer: The case results described above are provided for informational purposes only and reflect outcomes achieved in specific matters handled by Marin & Murphy. Prior results do not guarantee, warrant, or predict a similar outcome in any future case. Each legal matter is unique, and the success of any case depends on its specific factual and legal circumstances, which may differ significantly from those in the cases referenced. No representation is made that the quality of legal services to be performed is greater than the quality of legal services performed by other lawyers. For a comprehensive evaluation of your potential claim, please contact our firm directly.